the ugg boots from all of the formulations

After shoeing, the ugg boots from all of the formulations had a good appearance. None of the tablets exhibited any signs of defects either during or after the shoeing trials. Tablets from all the batches passed the acid phase of dissolution testing with no release of ASA after 2 hours in 0.1 N HCL. During the buffer phase of testing (pH=6.80, as with the unshoeed tablet dissolution results, only the tablets containing just MCC and ASA failed to meet the USP specification of not less than 80% ASA released in 90 min. In fact, the other five formulations attained 80% ASA release in less than 20 min. After 3 months of storage at 40 degrees uggs boots, some of the tablets containing CCS or SSG exhibited softening of the film shoeing and sticking of the tablets to one another within the HDPE bottles. This occurred in the samples that were packaged both with and without desiccant packs. Any tablets exhibiting signs of defects at this point were considered stability failures. The free salicylic acid results for the shoeed tablets were very similar to those results obtained for the unshoeed tablets. The north face denalilimit for the free salicylic acid in shoeed ASA tablets, 3.0%, is higher than the unshoeed tablet specification. After 3 months in accelerated conditions, the tablets containing just MCC as the excipient exhibited higher, but acceptable, free salicylic acid levels.
Par golfs le mardi 26 juillet 2011

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